許智能 Sodio Chih-Neng Hsu

教授兼總務長

生物無機/有機金屬化學

高雄醫學大學 醫藥暨應用化學系

Lab: (886) 7-3121101 Ext. 6984 (實驗室)

Office: (886) 7-3121101 Ext. 2123 (總務處)

Fax: (886) 7-3125339

Email: sodiohsu@kmu.edu.tw

ORCID http://orcid.org/0000-0002-2576-7289

 

研究方向及成果:

1.      設計及合成銅配位化合物模擬的生物系統中的銅化學

2.      金屬氰基及異氰基的自組裝化學

3.      金屬藥物的設計及合成

 

教育:

國立中山大學化學研究所博士(1998)

國立中山大學化學研究所碩士(1994)

淡江大學化學系理學士(1992)

 

工作與研究經歷

10/2020-            高雄醫學大學總務長

8/2013-              高雄醫學大學醫藥暨應用化學系教授

8/2015-10/2020   高雄醫學大學醫藥暨應用化學系系主任

8/2013-7/2015         高雄醫學大學學生事務處職涯輔導組組長

8/2009-7/2013      高雄醫學大學醫藥暨應用化學系副教授

8/2010-7/2012         高雄醫學大學學生事務處生活輔導組組長

8/2009-7/2011         高雄醫學大學學生事務處僑生暨外籍生輔導組組長

8/2002-7/2009         高雄醫學大學醫藥暨應用化學系助理教授

9/2000-7/2002         University of Illinois-Champaign/Urbana, 博士後研究員

4/2000-8/2000         中央研究院博士後研究員

 

社團活動與榮譽

2019年台灣生物無機學會傑出青年學者獎

國科會獎勵特殊優秀人才(2010~2013)

科技部獎勵特殊優秀人才(2014~2017)

教育部特殊優秀教學人才獎勵(2012~2019)

台灣生物無機學會理事

中國化學會會員

美國化學學會會員

 

研究與教學計畫

2002~迄今 國科會及科技部研究計畫主持人

2017~2020 教育部「優秀外國青年來臺蹲點計畫(TEEP)」整合型計畫主持人

2017~2020 教育部新南向計畫印度專班主持人

2017~2018 高雄醫學大學高等教育深耕計畫執行委員會副執行秘書

2016~2017 科學園區人才培育計畫主持人

2013~2015 高雄醫學大學教學卓越計畫主軸三「產學攜手職涯加值」副召集人

2011~2012 高雄醫學大學公民陶朔計畫主軸六「校園生活學習圈」召集人

2010~2012 高雄醫學大學教學卓越計畫主軸六「國際A+人才揚升」副召集人

2010 教育部「大學跨學門人才培育銜接計畫」主持人

2009~2010教育部顧問室發展型計畫:「開發生物體重金屬離子及其環境污染分佈之螢光偵測方法」主持人

2005 教育部顧問室「基礎科學前瞻性人才培育計畫」主持人

 

Selected Publications(學術論文發表):

1.      Huang, Y.-T.; Lan, W.-Y.; Ching, W.-M.; Tsai, M.-L.; Hsu, S. C. N.* “Formation of Iron(III)-Thiolate Metallocyclophane Using a Ferrocene-Based Bis-Isocyanide” New J. Chem., 2020, Accepted Manuscript https://doi.org/10.1039/D0NJ03967E

2.      Narwane, M.; Chang, Y.-L.; Ching, W.-M.; Tsai, M.-L.; Hsu, S. C. N.*Investigation on the Coordination Behaviors of Tris(2-pyridyl)pyrazolyl Borates Iron(II) ComplexesInorganica Chim. Acta 2019, 495, 118966.

3.      Huang, Y.-T.; Haribabu, J; Chien, C.-M.; Sabapathi, G; Chou, C.-K.; Karvembu, R.; Venuvanalingam, P.; Ching, W.-M.; Tsai, M.-L.; Hsu, S. C. N.* “Half-sandwich Ru(η6-p-cymene) complexes featuring pyrazole appended ligands: Synthesis, DNA binding and in vitro cytotoxicityJ. Inorg. Biochem. 2019, 194, 74-84.    

4.      Chuang, W.-J.; Narwane, M.; Chen, H.-Y.; Kao, C.-L.; Huang, B.; Hsu, K.-M.; Wang, Y.-M.*; Hsu, S. C. N.*Nitric Oxide Release Study of a Bio-inspired Copper(I)-nitrito Complex on Chemical and Biological ConditionsDalton Transactions, 2018, 47, 13151-13157.

5.      Chang, Y.-L.; Lin, Y.-F.; Chuang, W.-J. Kao, C.-L.; Narwane, M.; Chen, H.-Y.; Chiang, M. Y.; Hsu, S. C. N.*Structure and Nitrite Reduction Reactivity Study of Bio-inspired Copper(I)-nitro Complexes in Steric and Electronic Considerations of Tridentate Nitrogen LigandDalton Transactions, 2018, 47, 5335-5341.  

6.      Chand, K.; Tsai, C.-L.; Chen, H.-Y.; Ching, W.-M.; Hsu, S.-P.*; Carey, J. R.*; Hsu, S. C. N.* “Improved Synthesis of Unsymmetrical N-aryl-N'-alkylpyridyl ß-Diketimines using Molecular Sieves and their Lithium Complexes” Eur. J. Inorg. Chem. 2018, 1093-1098. This article was selected as a very important paper (VIP).

7.      Kosuru, S. R.; Sun, T.-H.; Wang, L.-F.; Vandavasi, J. K.; Lu, W.-Y.; Lai, Y.-C.; Hsu, S. C. N.*; Chiang, M. Y.*; Chen, H.-Y.* “Enhanced Catalytic Activity of Aluminum Complexes for the Ring-Opening Polymerization of ε-Caprolactone” Inorg. Chem., 2017, 56, 7998-8006

8.      Chuang, W.-J.; Hsu, S.-P.; Chand, K.; Yu, F.-L.; Tsai, C.-L.; Tseng, Y.-H; Lu, Y.-H.; Kuo, J.-Y.; Carey, J. R. Chen, H.-Y.; Chen, H.-Y.; Chiang, M. Y.; Hsu, S. C. N.* “Reactivity study of unsymmetrical βdiketiminato copper(I) complexes: effect of the chelating ring” Inorg. Chem. 2017, 56, 2722-2735

9.      Chuang, W.-J.; Chen, H.-Y.; Chen, W. T.; Chang, H.-Y.; Chiang, M. Y.; Chen, H.-Y.*; Hsu, S. C. N.* “Steric and chelating ring concerns on the L-lactide polymerization by asymmetric b-diketiminato zinc complexes” RSC Adv., 2016, 6, 36705-36714.

10.  Chuang, W.-J.; Huang, Y.-T.; Chen, Y.-H.; Lin, Y.-S.; Lu, W.-Y.; Lai, Y.-C.; Chiang, M. Y.*; Hsu, S. C. N.*; Chen, H.-Y.* “Synthesis, characterization, and catalytic activity of sodium ketminiate complexes toward the ring opening polymerization of L-lactide” RSC Adv., 2016, 6, 33014-33021.

11.  Chen, Y.-H.; Chen, Y.-J.; Tseng, H.-C.; Lian, C.-J.; Tsai. H.-Y.; Lai, Y.-C. Hsu, S. C. N.*; Chiang, M. Y.*; Chen, H.-Y.* “Comparing L-lactide and 3-caprolactone polymerization by using aluminum complexes bearing ketiminate ligands: steric, electronic, and chelating effects” RSC Adv., 2015, 5, 100272-100280

12.  Chen, Y.-H.; Lin, T. T. Y.; Chen, H.-Y.; Kao, C.-L.; Chen, H.-Y.; Hsu, S. C. N.*; Carey, J. R.; Chiang, M. Y. “A simple competition assay to probe pentacopper(I)-thiolato cluster ligand exchange” J. Inorg. Biochem. 2013, 120, 24-31.

13.  Hsu, S. C. N.*; Chang, Y.-L.; Chuang, W.-J.; Chen, H.-Y.; Lin, I. J.; Chiang, M. Y.; Kao, C.-L.; Chen, H.-Y. “Copper(I) Nitro Complex with an Anionic [HB(3,5-Me2Pz)3] Ligand: A Synthetic Model for the Copper Nitrite Reductase Active SiteInorg. Chem. 2012, 51, 9297-9308.

14.  Su, C.-J.; Tang, Y.-H.; Yu, F.-L.; Wu, R.-R.; Hsu, S. C. N.*; Kao, C.-L.*; Huang, H.-Y.; Chen, P.-Y.* “Extraction of Cupric Ions with Ionic Liquids Containing Polypyridine-type Small Molecules or Peripherally Pyridine-modified Dendrimers” Chemistry – An Asian Journal 2012, 7, 2438-2445.

15.  Lin, P.-C.; Chen, H.-Y.; Chen, P.-Y.; Chiang, M.-H.; Chiang, M. Y.; Kuo, T.-S.; Hsu, S. C. N.* “Self-Assembly and Redox Modulation of the Cavity Size of an Unusual Rectangular Iron Thiolate Aryldiisocyanide Metallocyclophane”Inorg. Chem. 2011, 50, 10825-10834.

This work provides a nice illustration of how the size of a self-assembled redox-active system can be controlled thanks to a redox stimulus, opening therefore interesting perspectives in terms of electrochemical-triggering of guest binding.” Comment by a feature article at Chem. Commun., 2015, 51, 7275-7289.

16.  Chuang, W.-J.; Lin, I-J.; Chen, H. Y.; Chang, Y.-L.; Hsu, S. C. N.* “Characterization of A New Copper(I)-ntirito Complex That Evolves Nitric Oxide” Inorg. Chem. 2010, 49, 5377-5384.